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Laboratory of Drug Discovery

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Indirubin derivatives having anticancer property against human cancer cell line
  • AuthorYong-chul Kim, Si Wouk Kim, Tae Sung Kim, Sang Kook Lee, Jae Il Kim, Jung-hoon Yoon, Sang-Gun Ahn, Myoung Ju Moon
  • Year2009
  • Source7572923

Structure–activity relationships of heteroaromatic esters as human rhinovirus 3C protease inhibitors
  • AuthorIsak Im, Eui Seung Lee, Soo Jeong Choi, Ju-Yeon Lee, Yong-Chul Kim
  • Year2009
  • SourceBioorganic & medicinal chemistry letters

Crystal structure of Rattus norvegicus Visfatin/PBEF/Nampt in complex with an FK866-based inhibitor
  • AuthorGil Bu Kang, Man-Ho Bae, Mun-Kyoung Kim, Isak Im, Yong-Chul Kim, Soo Hyun Eom
  • Year2009
  • SourceMolecules and cells

Anti-tumor activity of noble indirubin derivatives in human solid tumor models In Vitro
  • AuthorSoo-Hyun Kim, Soo Jeong Choi, Yong-Chul Kim, Hyo-Jeong Kuh
  • Year2009
  • SourceArchives of pharmacal research

Combinatorial Library Synthesis and Biological Evaluation of Pyrazolo[4,3‐e][1,4]diazepine as a Potential Privileged Structure
  • AuthorJu‐Yeon Lee, Yong‐Chul Kim
  • Year2009
  • SourceChemMedChem: Chemistry Enabling Drug Discovery

Crystallization and Preliminary X-Ray Crystallographic Studies of Rattus norvegicus Visfatin/PBEF/Nampt in Complex with an FK866-Based Inhibitor
  • AuthorMun-Kyoung Kim, Man-Ho Bae, Isak Im, Gil Bu Kang, Hye-Eun Song, Yongseong Kim, Jang-Soo Chun, Yong-Chul Kim, Soo Hyun Eom
  • Year2009
  • SourceBull. Korean Chem. Soc

Novel small molecule activators of β-catenin-mediated signaling pathway: structure–activity relationships of indirubins
  • AuthorEun-Jung Park, Soo Jeong Choi, Yong-Chul Kim, Sang Hyung Lee, Seoung Woo Park, Sang Kook Lee
  • Year2009
  • SourceBioorganic & medicinal chemistry letters

Inhibition of intestinal motility by the putative BKCa channel opener LDD175
  • AuthorIke Campomayor dela Peña, Seo Young Yoon, Sung Mok Kim, Geum Seon Lee, Chul-Seung Park, Yong Chul Kim, Jae Hoon Cheong
  • Year2009
  • SourceArchives of pharmacal research

Stereoselective synthesis and osteogenic activity of subglutinols A and B
  • AuthorHyoungsu Kim, Joseph B Baker, Su-Ui Lee, Yongho Park, Kyle L Bolduc, Hyung-Bae Park, Marina G Dickens, Dong-Sup Lee, Yongchul Kim, Seong Hwan Kim, Jiyong Hong
  • Year2009
  • SourceJournal of the American Chemical Society

Mechanism of Benzofuroindole-induced Potentiation of BKCa channel
  • AuthorByoung-Cheol Lee, Hyun-Ho Lim, Yong-Chul Kim, Chul-Seung Park
  • Year2009
  • SourceBiophysical Journal
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